At Clearsynth,

Our CDMO activities help in..



Focused process transformation...
WE SOLVE PROBLEMS!

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Our Story

We aspire to work on products and processes that are complex and hazardous.

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Our diverse and vast ‘Organic Chemistry’ experience in the field of synthesizing and characterizing reference standards like Drug Impurities, Metabolites, Gluconarites, Secondary API standards and stable Isotope Labelled compounds, has caused a need for taking much higher responsibilities of solving problems !

The challenges & complexities around unsafe reactions, Environmental pollution, Low yields, Multiple steps synthesis, Un-Viable cost, Material handling Hazard and Dependability, inspires us towards accomplishing our mission “to deliver sustainable products”

At Clearsynth, we thoroughly study, innovate, transform and implement processes that are just not novel, but also sustainable!

Our mission is not to sell products, we believe in SOLVING PROBLEMS.......

Meet our

Passionate team



100

+

Years of combined industry experience

R&D

Our State of Art R&D centre at Hyderabad is well equipped with 100+ Research scientists.

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The sophisticated analytical lab houses- LCMS, GCMS, TGA, Prep. HPLC, UPLC, NMRs, ELSD, PDA & RI Detectors, Chiral separation columns that enable our scientists to develop and transform any process at a record breaking speed of 10-14 weeks…
Ready for Tech transfer….

Manufacturing

Our Flow Chemistry lab is set to break all records in transforming batch processes.

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Our Kilo Lab, Pilot Plant and Multiple-product large scale cGMP manufacturing facility can take up projects involving diverse reactions like – Grignard, Hydrogenation, Nitration, Bromination, Enzymatic, Cyclization, Alkylation, Friedel Craft, Diazo-coupling, Hydrolysis, Catalytic reductions, Methylation, oxidation, fluorination, etc… Soon we are setting up a fixed bed catalytic reaction.

Our Flow Chemistry lab is set to break all records in transforming batch processes into continuous. We see number of products getting commercialized… Some of them are also first time in India by Clearsynth. We see this as a WAY FORWARD !

PRODUCTS

Chemical Name CAS No. API Name
2-Cyano-4'-methylbiphenyl (OTBN) 114772-53-1 Losartan
2Butyl4Chloro5Formylimidazole (BCFI) 83857-96-9 Losartan
2-Chloromethyl-3,4-dimethoxypyridinium chloride 72830-09-2 Pantoprazole
5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole 97963-62-7 Pantoprazole
4-Chloro-3-methoxy-2-methylpyridine 107512-34-5 Pantoprazole
5-Chlorothiophene-2-carboxylic acid 24065-33-6 Rivaroxaban
(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride 898543-06-1 Rivaroxaban
(S)-(+)-N-(2,3-Epoxypropyl) Phthalimide 161596-47-0 Rivaroxaban
1-Methoxy Empagliflozin (Methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-alpha-D-glucopyranoside) 1279691-36-9 Empagliflozin
4-Hydroxyquinoline-3-carboxylic acid 34785-11-0 Ivacaftor
5-amino-2,4-di-tert-butylphenyl methyl carbonate 1182822-31-6 Ivacaftor
3-(4-Tert-Butoxycarbonylamino-phenyl)-3-oxo-propionic acid ethyl ester 1017781-45-1 NCE
Methapyrilene hydrochloride 135-23-9 API
2-​Pyrimidinemethanamin​e 75985-45-4 Avanafil
Ethyl 2-[trans-4-[(tert-Butoxycarbonyl)amino]cyclohexyl]acetate 946598-34-1 Cariprazine
Bis (p-anisyl) Iodonium Iodide Bis (4-methoxy phenyl) Iodonium Iodide 6293-71-6 Levothyroxine
(R)​-​3-​Aminobutan-​1-​ol 61477-40-5 Dolutegravir
Aminoacetaldehyde dimethyl acetal 22483-09-6 Dolutegravir
N-Ethyl-1-(4-methoxyphenyl)propan-2-amine 14367-46-5 Mebeverine
Methyl trans-​3-​(4-​methoxyphenyl) Glycidate 42245-42-1 Diltiazem
Cyclopropane sulfonam​ide 154350-29-5 Simeprevir
bis(p-​methoxyphenyl)​iodonium bromide 19231-06-2 Levothyroxine
N-Acetyl-3,5-diiodo-l-tyrosine ethyl ester 21959-36-4 Levothyroxine
Ethyl 2-acetamindo-3-(3,5-diiodo-4-(4- methoxyphenoxy)phenyl) propanoate 83249-56-3 Levothyroxine
3,5-Diiodo-L-thyronine 1041-01-6 Levothyroxine
Liothyronine 6893-02-3 Levothyroxine
3-Benzyl-2,3,4,5-tetrahydro-1H-1,5- methanobenzo[d]azepine 230615-48-2 Varenicline
1-(4,5-Dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone 230615-51-7 Varenicline
3-​(Trifluoroacetyl)​-​7,​8-​dinitro-​4,​5-​dihydro-​1H-​1,​5-​methanobenzo[d]​azepine 230615-59-5 Varenicline
1-​(9,​10-​Dihydro-​6H-​6,​10-​methanoazepino[4,​5-​g]​quinoxalin- ​8(7H)​-​yl)​-​2,​2,​2-​trifluoroethanone 230615-70-0 Varenicline

SUSTAINABILITY

Our wisdom lies in Circular Economy We are passionate for it... for it's every bit.

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We truly believe that, for any process to be sustainable, one has to Re-cover, Re-use and Re-enrich. Our processes for manufacturing Bulk Deuterated Reagents & Building blocks does it all !

Our Team at Clearsynth has made us feel proud as in a true sense we have accomplished - IMPORT SUBSTITUTION, CIRCULAR ECONOMY AND SUSTAINABILITY.

Let's Get In Touch

Office Location

Give us a shout & we are happy to solve your problem.